Evaluation Of Cytotoxicity Of Root Sample Of Shankapushpi (Clitoria Ternatea) In Breast Cancer Cells (MCF-7)

Abstract

Breast cancer remains a leading cause of cancer-related mortality worldwide, necessitating the exploration of novel therapeutic agents. The search for effective anti-cancer agents from natural sources is an ongoing endeavor in cancer research. This study aimed to evaluate the anti-cancerous properties of the root extract of Shankapushpi (Clitoria ternatea), a traditional Ayurvedic herb renowned for its cognitive-enhancing, anxiolytic, and neuroprotective properties on human breast cancer cells. We investigated the cytotoxic effects of the root extract on MCF-7 breast cancer cell lines using various in vitro assays. Contrary to our expectations, the results indicated that Shankapushpi root extract did not exhibit significant cytotoxicity or inhibit the proliferation of breast cancer cells. These findings suggest that the root of Shankapushpi lacks efficacy in inhibiting breast cancer cell growth under the conditions tested. Further research is necessary to explore other parts of the plant or different extraction methods that might yield more promising anti-cancer properties.