Development of targeted drug delivery systems of combination therapy for treatment of H. Pylori infection

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Priya Jain
Rajesh Nagar
Sachin Kumar Jain
Sudha Vengurlekar

Abstract

Helicobacter pylori infection causes chronic gastritis, which can progress to severe gastroduodenal pathologies, including peptic ulcer, gastric cancer and gastric mucosa-associated lymphoid tissue lymphoma. H. pylori is usually transmitted in childhood and persists for life if untreated. The infection affects around half of the population in the world but prevalence varies according to location and sanitation standards. H. pylori have unique properties to colonize gastric epithelium in an acidic environment. The pathophysiology of H. pylori infection is dependent on complex bacterial virulence mechanisms and their interaction with the host immune system and environmental factors, resulting in distinct gastritis phenotypes that determine possible progression to different gastroduodenal pathologies.


 

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How to Cite
Priya Jain, Rajesh Nagar, Sachin Kumar Jain, & Sudha Vengurlekar. (2024). Development of targeted drug delivery systems of combination therapy for treatment of H. Pylori infection. Educational Administration: Theory and Practice, 30(10), 925–930. https://doi.org/10.53555/kuey.v30i10.10565
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Articles
Author Biographies

Priya Jain

Research Scholar, Faculty of Pharmacy, Oriental University, Indore (M.P.)

Rajesh Nagar

Faculty of Pharmacy, Oriental University, Indore (M.P.)

Sachin Kumar Jain

Faculty of Pharmacy, Oriental University, Indore (M.P.)

Sudha Vengurlekar

Faculty of Pharmacy, Oriental University, Indore (M.P.)